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Degenerative Spinal Disorders

What are Degenerative Spinal Disorders?

Degenerative spinal disorders are a group of conditions that involve a loss of normal structure and function in the spine. These common disorders are associated with the normal effects of aging, but also may be caused by infection, tumors, muscle strains, or arthritis.

Pressure on the spinal cord and nerve roots associated with spinal degeneration may be caused by disc displacement or herniation; spinal stenosis, a narrowing of the spinal canal; or osteoarthritis, cartilage breakdown at spinal joints.


The discs between the bones of the spine are made up of cartilage, fibrous tissue, and water. With age these discs can weaken and may flatten, bulge, break down, or herniate. Disc herniation, a common cause of pain associated spinal degeneration, occurs when the fibrous portion of a disc weakens and the disc nucleus pushes through and puts pressure on nearby nerves. In addition, a degenerating disc also may cause bony growths that can place additional pressure on the spinal cord.

Spinal stenosis, or narrowing of the spinal canal, is a condition potentially more serious than degenerative disc disease. As the spinal canal tightens, the spine and nerves may be significantly compressed and irritated, causing both back pain and pain that radiates to other parts of the body, depending on the location of the pressure on the nerves.


The primary symptoms of degenerative spinal disorders are sharp and/or chronic pain in the back and legs, weakness, limited motion, and sensory loss. If spinal degeneration leads to compression or injury of the spinal cord, weakness and limited motion may increase significantly. Loss of bladder and bowel function and problems with sexual function also may occur as the problem worsens. The specific symptoms often depend on the location of the structural problem in the spine.


Diagnosis often begins with a spinal x-ray, which does not show the discs but can show other bony changes in the spine. Magnetic resonance imaging (MRI) scans are the primary means of diagnosis because they can show the disc in detail and allow physicians to see the nerves and spinal canal space and how they are affected by the disease. Computed tomography (CT) scans also may be used.

However, the diagnosis of back problems, even with MRI, can be difficult by the presence of findings that do not correlate well with a patients symptoms.


Treatment for degenerative spinal disorders depends on the severity of the condition. In most cases, the problem is not severe enough to require invasive treatment. The first line of treatment is activity modification, oral pain medication, and physical therapy to strengthen the muscles of the back and improve flexibility and range of motion.

In addition, such as epidural injections of steroids or pain medication, may be used to isolate the source of pain and provide temporary pain relief?making physical therapy more productive in patients with severe pain. Noninvasive and minimally invasive procedures will provide pain relief for the vast majority of patients.

Surgery may eventually be necessary as a condition progresses. Surgery is indicated in patients with chronic severe pain, nerve deficits, and loss of bladder and bowel control. Also, surgery may be considered in patients who have not responded to less invasive treatment and in patients who have an identifiable structural abnormality that can be effectively corrected.

Surgical procedures used vary depending on the type of condition and its severity. In some patients, a herniated disc can be surgically repaired to restore the normal anatomic structure. In other patients the disc that is causing pain or the bone placing pressure on the spinal cord must be removed. In patients with spinal stenosis for example, only surgery to alleviate the pressure on the spinal cord can provide relief of notable duration.

The vertebrae may also need to be stabilized through a process called spinal fusion. Metallic devices are used to stabilize the spine, and then bone taken from another part of the body or from a bone bank is implanted to encourage bone to grow across the span. Bone growth may be encouraged with bone morphogenetic protein, a biologic product that stimulates the creation of new bone.

The results of surgery usually are excellent and most patients return to normal function in a matter of weeks.